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Hydrelle (Elevess) Dermal Filler

Marketed by Coapt Systems, Inc., and manufactured by Anika Therapeutics, Hydrelle (formerly known as Elevess), was approved by the Food and Drug Administration in 2009 for use in the United States. Hydrelle is a hyaluronic based dermal filler, complete with lidocaine, making injections more comfortable,and used to create volume in the skin, decreasing deeper facial lines and wrinkles.


How It Works

Hydrelle is a cross-linked hyaluronic acid-based dermal, facial filler, in injectable gel form. Cross-linking is a process used to make hyaluronic acid into a gel product, which can be injected into the dermis, for a longer-lasting effect on the skin. Hyaluronic acid is a natural component of skin, and has the ability to retain moisture, and to form complexes with elastin and collagen in the skin. Hyaluronic acid supports structure of the skin, contributes to skin’s elasticity, and creates volume, pushing wrinkles and folds out.

Age, sun exposure, lifestyle, and disease lead to decreased production of hyaluronic acid in the skin, which results eventually in decreased facial skin volume, and the appearance of unwanted wrinkles. Hydrelle/Elevess contains the highest concentration of hyaluronic acid of the dermal fillers approved for use in the United States, is cross-linked for lasting results, and contains lidocaine, improving injection comfort.

Benefits of Hydrelle

  • Can treat deeper lines and wrinkles with fewer injections (nasolabial folds, fine lines around the eyes and mouth) and provides immediate results
  • Little to no risk of having an allergic reaction, because it is made of hyaluronic acid and a pre-test on the skin is not required
  • Less painful than other dermal fillers, because it contains lidocaine (anesthetic) in the gel
  • Fast recovery time with symptoms lasting usually only one week
  • Can be used for facial contouring such as cheek enhancement, and lip enhancement
  • No major side effects experienced in clinical trials
  • No downtime, and if any side effects such as swelling or slight bruising occur, these will usually diminish withing 24-48 hours
  • Price is more affordable than other fillers, because it is in concentrated form, requiring 50% less than other dermal fillers of its kind ($400-600 range usually)

The Injection Procedure

It is important before the procedure, to consult with a doctor who is experienced in administering dermal injections, to evaluate your skin and past medical history. The administrator, and how your skin reacts to the injections will be a determining factor in the success of any injection. The injections are made at various scored points on the face after cleansing, and because lidocaine is contained in the injection, topical anesthetic may or may not be used. The procedure can take under an hour, with consultation, and there is usually no down time.

Side Effects And Possible Complications

Some common side effects may be swelling, redness, bruising, tenderness, itching, and small bump (nodule) formation, but these effects usually last less than one week. The skin should not be over-exposed to sun, ultra-violet rays, or extreme cold initially after treatment. If you have had laser, chemical, or any other dermal treatments, injections may be postponed until your skin has completely recovered. Treatment may also be postponed if you have inflammatory skin problems, such as sores, cysts, rashes, hives or infections.

Because Hydrelle contains sodium metabisulfite as an antioxidant, and contains trace amounts of gram positive bacteria, certain people may have allergic reactions. If you have a history of anaphyalaxis (severe allergies), are taking anti-coagulant drugs (blood-thinners), are pregnant or nursing, or undergoing immunosuppressive therapy, you may need to choose an alternative treatment.

Hydrelle Filler Reviews

The reviews for Hydrelle dermal filler are mostly negative, with a few positive results interspersed. The negative reviews come from patients who experienced severe reactions to the injections, with painful swelling, and blistering of the face. Many of the patients did not have known allergies, and were very surprised and depressed by the reaction that the injections had in the skin. Doctor reviews suggest only using Hydrelle for thicker skin injections, and that the injections must be deep enough in the dermal layer of skin, under the wrinkles.

The injections may be removed with the hyaluronidase enzyme, but many patients had to take other prescribed medications, not only to treat swelling, but also because of the risk of infection. The bottom line is to discuss possible reactions with your doctor, and to discuss alternatives. The method of injecting any dermal filler, the consistency of your skin and the severity of facial wrinkles to be treated, all play a part in the success of any facial, dermal filler injections.

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