Esthelis Soft and Esthelis Basic are two dermal fillers in the hyaluronic acid based ranges of cosmetic treatments. Esthelis was approved by the Food and Drug administration in 2011 for use in the United States, and is used to treat fine lines and wrinkles, while assisting in skin rehydration. It was approved under the name Belotero, manufactured by Anteis, and distributed under the name Esthelis by Merz Aesthetics. It is the first monophasic hyaluronic acid filler using a patented CPM technology, which sets it apart from the conventional monophasic hyaluronic acid dermal fillers.
What Makes Esthelis Filler Different
Esthelis is made from non-animal hyaluronic acid, yet the way in which it is chemically produced, differentiates it from other hyaluronic acid fillers. Cohesive Polydensified Matrix (CPM) is a patented technology used to make Esthelis. CPM double cross-links monophasic hyaluronic acid strands with Butanediol Diglycidyl Ether (BDDE) which is the stabilizer. Linking the hyaluronic acid chains, allows it to slow down degradation, making the product last longer.
Esthelis integrates into the tissue surrounding it in the dermal layer of skin, and provides a smoother transition between the treated, and non-treated areas. It can also be used in the most superficial dermal layers, by using less product. Esthelis contains glycerol to increase skin elasticity, and rehydrates the skin, improving skin tone. The glycerol in Esthelis coats and protects the hyaluronic acid from free radicals, enzymes, and thermal degradation in the body.
Features Of Esthelis Dermal Filler
There are two ranges of Esthelis: Esthelis Basic, and Esthelis Soft. There is also a package just for men. Anteis stresses that the precision of the injection, and the biointegration of the product, are the two factors of successful dermal filling to correct facial wrinkles.
Esthelis Soft is injected into the superficial to middle dermis and treats:
- Fine wrinkles
- Perioral wrinkles around the lips and mouth
- Lip commisures
- Crows feet
- Forehead wrinkles
- Facial depressions or scars
Esthelis Basic is injected into the middle to deep dermis and is used for:
- Lip augmentation
- Facial outlining/contouring
- Glabellar lines
- Nasolabial furrows
- Facial depressions or scars
The Injection Procedure And Side Effects
Because successful dermal filler treatment relies on the precision of injection, Anteis has developed the Anteis Injection System, which is fully automated. The fine gauge needle allows for more even product placement, varied angles and depths of placement, and better control over the speed and amount of injections. This reduces the patient’s pain, and also may reduce the occurrence of side effects from the injections.
The injection procedure requires consulting with a doctor, experienced in dermal filler injections. Medical history and any medications you are taking need to be discussed, as well as your expectations. The face is cleansed, marked for injection sites, and injections are administered. This process takes usually less than an hour, and there is usually little if any down time. Because Esthelis is made of hyaluronic acid, there is no allergy pre-test required. Treatments are on average, approximately $500.
If you have a history of severe allergic reactions, are pregnant or breastfeeding, are taking anti-coagulant drugs, or are on immunosuppressive treatments, you should discuss alternative treatments with your doctor. Common side effects may be redness, swelling, itching, discomfort, and discoloration for 24-48 hours. If you are receiving lip injections, these symptoms may last a week. Immediately following injections, it is recommended to avoid over exposure to the sun, ultraviolet rays, and massaging the injected area.
Esthelis/Belotero seems to work nicely for lip augmentation, but at this time, there are too few results reviewed on this product for uses on other facial wrinkles and folds. The clinical study group had very few lingering side effects, and the product developed fewer visible lumps. Esthelis seems to inject more smoothly and evenly, making a less noticeable, but definite and longer-lasting improvement.